Lab members | Equal contribution
2022
Mahajan S and Agashe D (2022). Evolutionary jumps in bacterial GC content. G3|Genes|Genomes|Genetics 12:jkac108. Preprint | Online access
Wahl LM and Agashe D (2022). Selection bias in mutation accumulation. Evolution 76: 528-540 Online Access | NCBS news article
2021
Samhita L, Raval PK, Stephenson G, Thutupalli S and Agashe D (2021). The impact of mistranslation on phenotypic variability and fitness. Evolution 75(5):1201-1217 Open Access | NCBS News article | Biopatrika interview
2020
Samhita L, Raval PK and Agashe D (2020). Global mistranslation increases cell survival under stress in E. coli. PLoS Genetics 16(3): e1008654 Open Access | NCBS news article | Recommended by Faculty of 1000
Sanjenbam P, Buddidathi R, Venkatesan R, Shivaprasad PV and Agashe D (2020). Phenotypic diversity of Methylobacterium associated with rice landraces in North-east India. PLoS One 15(2): e0228550 Open Access
2019
Kaminski Strauss S, …, Agashe D, …, Walunjkar N, …. and Yitzak Pilpel [total 63 authors] (2019). Evolthon: A community endeavor to evolve lab evolution. PLoS Biology 17(3): e3000182 Open access
2018
Sane M, Miranda JJ and Agashe D (2018). Antagonistic pleiotropy for carbon use is rare in new mutations. Evolution 72(10):2202-2213 Open access | NCBS News article
Diwan GD and Agashe D (2018). Wobbling forth and drifting back: The evolutionary history and impact of tRNA modifying enzymes. Molecular Biology and Evolution 35(8):2046-2059 Open access | NCBS News article
| GBE Special issue on synonymous mutations
2017
Agashe D (2017). The road not taken: Could stress-specific mutations lead to different evolutionary paths? PLoS Biology 15(6): e2002862 Open access
2016
Diwan GD and Agashe D (2016). The frequency of internal Shine-Dalgarno – like motifs in prokaryotes. Genome Biology and Evolution 8(6):1722-1733 Open access
Agashe D, Sane M, Phalnikar K, Diwan GD, Habibullah A, Martinez-Gomez NC, Sahasrabuddhe V, Polachek W, Wang J, Chubiz L and Marx CJ (2016). Large-effect beneficial synonymous mutations mediate rapid and parallel adaptation in a bacterium. Molecular Biology and Evolution 33: 1542-1553. Open access | MBE News
Nayak DD, Agashe D, Lee M-C and Marx CJ (2016). Selection maintains apparently degenerate metabolic pathways due to tradeoffs in using methylamine for carbon versus nitrogen. Current Biology 26:1416-1426 PDF
2015
Carroll SM, Chubiz LM, Agashe D and Marx CJ (2015). Parallel and divergent evolutionary solutions for the optimization of an engineered central metabolism in Methylobacterium extorquens AM1. Microorganisms 3:152-174 PDF
2014
Agashe D and Shankar N (2014). The evolution of bacterial DNA base composition. Journal of Experimental Zoology, series B 322 (7): 517-528 PDF
2009–2013
Agashe D, Martinez-Gomez NC, Drummond DA and Marx CJ (2013). Good codons, bad transcript: large reductions in gene expression and fitness arising from synonymous mutations in a key enzyme. Molecular Biology and Evolution 30(3): 549-560 PDF | SI | Recommended by Faculty of 1000
AdaptationLab 