Organisms often face new, changing or otherwise challenging environments, which can drive evolutionary adaptations. However, different populations and species often respond differentially to the same environmental change, potentially altering their evolutionary trajectories. For instance, some organisms flourish in new environments, whereas others go extinct. What factors determine individual and population-level responses, and what are the... Continue Reading →
Mutational signatures in wild E coli
Bacterial genomes experience lots of mutations that result from a complex mix of DNA damage, errors made by DNA polymerase, and errors repaired or made by repair enzymes. Do these processes leave a tell-tale signature in the genome, and can we use it to infer which processes were most important? A new paper in Genome... Continue Reading →
New funding and open postdoctoral positions
We are very happy that the lab now has more funds to support our work on the evolution and consequences of mutation bias, in the form of a DBT/Wellcome Trust India Alliance Senior Fellowship to Deepa. The generous funding means that we will soon be hiring two postdoctoral fellows to join our group and work... Continue Reading →
Shivansh wins poster prize
The lab had a great showing at the 2024 NCBS Annual talks, with three exciting posters from Pratibha and Harshith (Ecological drift in the flour beetle gut microbiome), Ruchith and Shazia (Mutation bias and tradeoffs), and Shivansh (The genetic basis of adaptation in flour beetles). These are all fun new stories from the lab that... Continue Reading →
Welcome Aakanksha!
We are very happy that Aakanksha Madhwal has joined the lab as a new PhD student. She has a Bachelor's degree in Microbiology from Graphic Era Deemed To Be University, Dehradun, and a Master's Degree in Biotechnology from Banaras Hindu University, Varanasi. Microorganisms have always piqued her interest, and she is curious about how these seemingly simple... Continue Reading →
Symposium Section in the American Naturalist
In 2022, Deepa organized the ASN Vice-Presidential Symposium at the annual meeting of the Evolution societies in Cleveland, Ohio, USA. The symposium featured a set of wonderful talks by five invited speakers from across the world, analysing how genetic variation shapes adaptation. The work reported in these talks is now out in the Symposium section... Continue Reading →
Welcome Shazia!
We're very happy to welcome Shazia Parveen, who worked with us as a JRF for some time and has now formally joined the lab as a PhD student. Shazia has a Bachelor's degree in Biotechnology from Jamia Millia Islamia New Delhi, and an MSc in Molecular Medical Microbiology from IIT Kharagpur. She is interested in using... Continue Reading →
Mark your calendar for the 6th Popgen school!
Happy to announce that applications are now open for the next Bangalore school on population genetics and evolution from 12–23 Feb, 2024. We welcome PhD students and postdocs interested in evolutionary biology, from India as well as other Asian and African countries. There are no participation fees, and we have some travel support for international... Continue Reading →
Diet microbiome has variable effects on different immune responses
Several years ago, Arun Prakash and Imroze Khan set up an ambitious experimental evolution study in the lab, infecting populations of flour beetles with the pathogen Bacillus thuringiensis (Bt). They found that different selection regimes led to the evolution of mutually exclusive immune responses – beetles either evolved better basal resistance to Bt, or immune priming... Continue Reading →