Welcome to Deepa Agashe’s lab at the National Centre for Biological Sciences (NCBS), Bangalore!

Organisms often face new, changing or otherwise challenging environments, which can drive evolutionary adaptations. However, different populations and species often respond differentially to the same environmental change, potentially altering their evolutionary trajectories. For instance, some organisms flourish in new environments, whereas others go extinct. What factors determine individual and population-level responses, and what are the... Continue Reading →

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New paper: Bacterial associates can increase rice yield

The results of our field study of the impact of different Methylobacterium strains on their host rice landraces (traditionally cultivated rice varieties from Manipur) are out! We find that strains show host-specific effects (beneficial or deleterious). Though the mechanisms remain unclear still, it is clear that there is enormous potential to use beneficial host-bacterial interactions for... Continue Reading →

Laasya starts faculty position

We are very happy that former lab member Laasya has joined Ashoka University as an Assistant Professor and will be building her group there to continue exploring themes of mistranslation and antimicrobial resistance. If you are interested in these areas of research, do consider joining her lab.

New paper: Pinning big jumps in genome GC

Bacteria have remarkably diverse base composition in their genomes, with many well studied cases of rapid GC reduction associated with obligate symbiosis and genome streamlining in poor environments. But we don't really understand how GC content generally changes in evolutionary time. To find out, Saurabh tested different evolutionary models of change in GC content in... Continue Reading →

Lab turns 10!

This month the lab completes a decade of existence. I am proud of all the fun science we have done as a group over the years, and the myriad ways in which all of us have grown. A lot of earlier themes are wrapping up and there are new exciting directions to pursue. Onward, to... Continue Reading →

Paper review: Resource allocation and tradeoffs

In the second installment of our series of reviews on the lab's favourite papers, Shubha Govindarajan writes about a classic paper that gave a new perspective on individual variation and tradeoffs. Read on! Fig 1 from van Noordwijk & de Jong 1986, American Naturalist Acquisition and Allocation of Resources: Their Influence on Variation in Life... Continue Reading →

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