Welcome to Deepa Agashe’s lab at the National Centre for Biological Sciences (NCBS), Bangalore!

Organisms often face new, changing or otherwise challenging environments, which can drive evolutionary adaptations. However, different populations and species often respond differentially to the same environmental change, potentially altering their evolutionary trajectories. For instance, some organisms flourish in new environments, whereas others go extinct. What factors determine individual and population-level responses, and what are the... Continue Reading →

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New paper: Mutation bias shifts can be adaptive

Our paper describing the evolutionary effects of shifts in mutation bias is now published! We started out by asking if mutation spectrum could alter the fitness effects of new mutations in E. coli. To our surprise, we found a consistent effect across many environments, but could not attribute the difference to any particular properties of... Continue Reading →

Rittik starts new faculty position

Former postdoctoral fellow Rittik Deb has joined the National Institute of Science Education and Research (NISER) Bhubaneswar as an Assistant Professor. Congratulations Rittik, and we look forward to all of the exciting discoveries that you and your group will make in the coming years!

New paper: Review on evolutionary prediction

In late 2019, a bunch of people gathered at the Lorentz Center in The Netherlands to think about how we can predict evolution, and what we need to do better. It was a fantastic meeting, and we just published one of the outcomes – a review discussing different kinds of evolutionary predictions, factors that increase predictability,... Continue Reading →

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