Several years ago, Arun Prakash and Imroze Khan set up an ambitious experimental evolution study in the lab, infecting populations of flour beetles with the pathogen Bacillus thuringiensis (Bt). They found that different selection regimes led to the evolution of mutually exclusive immune responses – beetles either evolved better basal resistance to Bt, or immune priming... Continue Reading →
New paper: Costs and benefits of evolved immune responses
Arun's paper reporting the detailed costs and benefits of evolved immune priming is now published! In an exciting earlier study, we had found that flour beetles exposed to the pathogen Bacillus thuringiensis adapted rapidly via the evolution of either immune priming or pathogen resistance. The new work – led by Arun (now at Edinburgh University)... Continue Reading →
New paper: Explaining population level variation in immune priming
Here's the latest from Imroze and Arun. A couple years ago we had found surprising levels of variability in immune memory ("priming"), across 10 wild-collected flour beetle populations (Khan et al 2016, Ecology and Evolution). In our new follow-up paper, we figured out what may explain this variation, by systematically analysing change in various fitness... Continue Reading →
