Our paper reporting the impact of selection bias in mutation accumulation (MA) experiments is now published! A few years ago, Mrudula had tested the effect of single mutations accumulated in MA experiments (see Sane et al 2018, Evolution), finding that a surprisingly large fraction were beneficial. In the new paper, mathematician Lindi Wahl uses simulations... Continue Reading →
Survey: challenges of establishing a research career in India
The Indian National Young Academy of Science (INYAS) conducted a survey of ~800 young scientists establishing an independent research career in India. The report and associated recommendations will hopefully guide positive change. Read the full report here.
New paper: Costs and benefits of evolved immune responses
Arun's paper reporting the detailed costs and benefits of evolved immune priming is now published! In an exciting earlier study, we had found that flour beetles exposed to the pathogen Bacillus thuringiensis adapted rapidly via the evolution of either immune priming or pathogen resistance. The new work – led by Arun (now at Edinburgh University)... Continue Reading →
Laasya interviewed on Biopatrika
Read Laasya's short interview about her work and career goals, and our paper on the phenotypic effects of mistranslation.
New paper: Mistranslation increases phenotypic variation
Our collaborative work (with Shashi Thutupalli’s lab at NCBS) on tracking mistranslation-induced phenotypic variability is now published! Protein sequences often differ because of underlying differences in DNA sequence (i.e. genetic mutations). However, making mistakes while building the protein can also introduce differences in the protein sequence, although at a low frequency. Proteins altered in this... Continue Reading →
New paper: Evolutionary effects of non-genetic inheritance
Laasya’s single-author review on how non-genetic changes can contribute to evolution is now out in Current Genetics! Transfer of information in biology usually occurs from nucleic acids to protein, but not vice-versa (The Central Dogma). Any molecular alteration that does not change the DNA sequence (genotype) is generally short lived, and is thought to have... Continue Reading →
New paper: Microbiome of a generalist pest
Apart from humans, many organisms acquire beneficial bacterial partners from the food that they eat. But what about generalists, whose diet can vary every day? We asked whether the bacteria in the diet of the red flour beetle – a grain pest found across the world – impact the beetles’ fitness in different diets. For... Continue Reading →
New paper: What do the colours of a female damselfly say?
Shantanu's work on female colour variation in the widespread, tiny damselfly Agriocnemis pygmaea is now out! Females of this damselfly (seen at the campus pond) come in two colors: red and blue, as well as a bunch of intermediate forms. We wondered whether these colours represent allelic forms, or ontogenic (age-related) change. From laboratory studies... Continue Reading →