Many key molecules in our cells are specific enantiomers, and their mirror image forms are not found in living beings. For instance, the sugars in DNA are all left-handed, while amino acids are right-handed. For decades, scientists have wondered whether a completely "flipped" mirror organism would be viable and how it would function. With major... Continue Reading →
Our recently completed multi-year project suggests that there is no straight answer to this question! We sampled the leaves of different rice varieties across 3 years, finding that bacterial communities that live inside vs. on the surface of leaves differ in many ways, and over time. As expected from greater exposure to environmental influences (including... Continue Reading →
A new study led by Tapomoy Bhattacharjee's group shows that rods vs. cocci grow in distinct ways in porous 3D matrices, and these differences make rods more robust to increasing matrix viscosity. Bacteria in natural habitats likely live in such matrices; indeed, the bacteria used in this study were isolated from flour beetle guts in our... Continue Reading →
We are looking to recruit a Postdoctoral Fellow with a start date of February or March 2025. The position is for a minimum of 2 years (extendable for up to 4 years), supported by an ongoing grant from the DBT/Wellcome Trust India Alliance to study the evolutionary effects of mutation bias. Salary and benefits will... Continue Reading →
Several years ago, Arun Prakash and Imroze Khan set up an ambitious experimental evolution study in the lab, infecting populations of flour beetles with the pathogen Bacillus thuringiensis (Bt). They found that different selection regimes led to the evolution of mutually exclusive immune responses – beetles either evolved better basal resistance to Bt, or immune priming... Continue Reading →
The results of our field study of the impact of different Methylobacterium strains on their host rice landraces (traditionally cultivated rice varieties from Manipur) are out! We find that strains show host-specific effects (beneficial or deleterious). Though the mechanisms remain unclear still, it is clear that there is enormous potential to use beneficial host-bacterial interactions for... Continue Reading →
We are happy to finally announce the 1st meeting of our special topic network on synthesizing micro- and macro- evolutionary processes shaping prokaryotic genomes, supported by ESEB. The meeting will be hosted at the Milner Center for Evolution at the University of Bath, UK, from 30 May to 1 June 2022. We have a great... Continue Reading →
Our paper reporting the impact of selection bias in mutation accumulation (MA) experiments is now published! A few years ago, Mrudula had tested the effect of single mutations accumulated in MA experiments (see Sane et al 2018, Evolution), finding that a surprisingly large fraction were beneficial. In the new paper, mathematician Lindi Wahl uses simulations... Continue Reading →
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